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	<title>TPP問題まとめ - 利用者の投稿記録 [ja]</title>
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Mutation of Tyr245 or Tyr305 in SET7/9 (Figure 4b ) alters its specificity from an H3 K4 mono-methylase to a tri- and di-methylase, respectively sixteen , 21 , whereas an Phe281Tyr mutation in the lysine-binding pocket of DIM-5 (Determine 4c ) converts this protein to an H3 K9 mono- or di-methylase sixteen These mutations exemplify the F/Y switch (Figure 1 ) that establishes SET-area product specificities.&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;The Every day Mail ran the story about a local council survey discovering 4,000 holes in the road in Lancashire in 1967. Methyltransferases are concerned in epigenetic gene regulation by covalent modification of histones. 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		<author><name>SadyeAbdullah98</name></author>
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